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1-Aminooctaethylene Glycol CAS NO 352439-37-3


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CAS No.:352439-37-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-Aminooctaethylene Glycol is a high-purity, hydrophilic bifunctional molecule featuring a primary amine group and a polyether chain. This structure is critical for creating stable, water-soluble conjugates and functional materials in advanced research and manufacturing. It is essential for scientists and engineers in the pharmaceutical, biotechnology, and specialty polymer industries who require reliable, high-quality linkers for PEGylation, bioconjugation, and surface modification.

Application

  • Pharmaceutical PEGylation: Acts as a versatile linker for attaching therapeutic proteins, peptides, or small molecule drugs to polyethylene glycol (PEG) chains to enhance solubility, stability, and circulation half-life.
  • Bioconjugation & Probe Synthesis: Used to functionalize antibodies, enzymes, or other biomolecules with fluorescent dyes, biotin, or other tags for diagnostics, imaging, and assay development.
  • Surface Functionalization: Enables the modification of nanoparticles, quantum dots, and solid supports (e.g., glass, gold) with amine-reactive groups to create biocompatible coatings or sensing platforms.
  • Hydrogel & Polymer Synthesis: Serves as a hydrophilic crosslinker or initiator in the synthesis of smart hydrogels, non-fouling coatings, and other functional polymeric materials.
  • Chemical Intermediate: A key building block for synthesizing more complex heterobifunctional PEG derivatives and specialty surfactants.

Basic Information

Product Name 1-Aminooctaethylene Glycol
CAS No. 352439-37-3
Molecular Formula C16H35NO8
Molecular Weight 369.45 g/mol
Synonyms 8-Amino-3,6,9,12,15,18,21,24-octaoxahexacosan-1-ol; Amino-PEG8-OH; α-Amino-ω-hydroxy-octa(ethylene glycol); H2N-PEG8-OH; 2-[2-[2-[2-[2-[2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethylamine; Octaethylene glycol monoamine; OEG8-amine; Amino octaethylene glycol
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Quality Control

Our 1-Aminooctaethylene Glycol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item Specification
Appearance Colorless to pale yellow viscous liquid
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 95.0%
Water Content (KF) ≤ 1.0%
Primary Amine Content (Titration) ≥ 90% of theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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