Description

4-(4-Bromo-Phenyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate crucial for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is valued for its role as a key building block in medicinal chemistry, enabling the introduction of a functionalized piperazine moiety into target molecules. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within central nervous system (CNS) and oncology research pipelines.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting neurological receptors.
• Organic Synthesis Reagent: Used in research-scale and process chemistry for constructing complex heterocyclic compounds and piperazine derivatives.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development and quality control in API manufacturing.
• Medicinal Chemistry Research: Enables structure-activity relationship (SAR) studies for the optimization of lead compounds in drug discovery programs.
• Precursor for Functionalized Ligands: Used in the development of specialized ligands for catalysis and biochemical assays.

Basic Information

Product Name	4-(4-Bromo-Phenyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	352437-09-3
Molecular Formula	C15H21BrN2O2
Molecular Weight	341.25 g/mol
Synonyms	tert-Butyl 4-(4-bromophenyl)piperazine-1-carboxylate; 1-Boc-4-(4-bromophenyl)piperazine; 4-(4-Bromophenyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; N-Boc-4-(4-bromophenyl)piperazine; 1-(tert-Butoxycarbonyl)-4-(4-bromophenyl)piperazine; 4-(p-Bromophenyl)-1-piperazinecarboxylic acid tert-butyl ester; 4-(4-Bromophenyl)piperazine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 4-(4-Bromo-Phenyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.