Description

Ho-Peg19-Oh CAS NO 351342-07-9 is a high-purity, heterobifunctional polyethylene glycol (PEG) derivative featuring a hydroxyl group at one terminus and a protected hydroxyl group at the other, designed for precise bioconjugation and linker applications. This compound is critical for creating stable, hydrophilic spacers that improve solubility and reduce immunogenicity in therapeutic and diagnostic agents. It is an essential building block for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require reliable, well-defined PEG linkers for drug delivery systems, protein modification, and surface functionalization.

Application

• Bioconjugation linker for attaching drugs, proteins, or fluorescent dyes.
• Hydrophilic spacer arm in Antibody-Drug Conjugates (ADCs) and peptide therapeutics.
• Surface modification agent for nanoparticles and medical devices to enhance biocompatibility.
• Intermediate in the synthesis of complex PEG derivatives and cross-linkers.
• Solubility enhancer for hydrophobic active pharmaceutical ingredients (APIs).
• Building block for hydrogel formation and polymer-based drug delivery platforms.
• Functionalization agent for biosensors and diagnostic assay components.

Basic Information

Item	Details
Product Name	Ho-Peg19-Oh
CAS No.	351342-07-9
Molecular Formula	C39H78O21
Molecular Weight	858.99 g/mol
Synonyms	19-Amino-4,7,10,13,16-pentaoxanonadecan-1-ol; Heterobifunctional PEG 1000 (HO-PEG19-NH2); α-Hydroxy-ω-amino PEG (n=19); 19-Amino-4,7,10,13,16-pentaoxanonadecanol; Amino-PEG19-alcohol; HO-PEG19-NH2; PEG 1000 derivative (amino, hydroxy); Poly(ethylene glycol) bis(3-aminopropyl) terminated (approximate Mn 1000)
EINECS	Contact for details

Quality Control

Our Ho-Peg19-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and biotech applications. Certificates of Analysis (COA) detailing purity, moisture content, and functional group analysis are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive). Allow the sealed container to reach room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white waxy solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Molecular Weight (GPC)	850 ± 50 g/mol
Functional Group Assay	≥ 90% (NH2, OH)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.