Description

tert-Butyl 4-(4-Aminobenzoyl)Tetrahydro-1(2H)-Pyrazinecarboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its specific piperazine and benzamide structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in areas requiring sophisticated heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders.
• API Synthesis: Serves as a core scaffold for constructing molecules with potential pharmacological activity in research and development pipelines.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Custom Synthesis Building Block: Employed by contract research and manufacturing organizations (CROs/CMOs) for the production of bespoke chemical entities for clients.
• Protease Inhibitor Development: Its structural features make it relevant for research into inhibitors of specific enzyme classes.

Basic Information

Product Name	tert-Butyl 4-(4-Aminobenzoyl)Tetrahydro-1(2H)-Pyrazinecarboxylate
CAS No.	350684-49-0
Molecular Formula	C16H23N3O3
Molecular Weight	305.37 g/mol
Synonyms	1-Boc-4-(4-aminobenzoyl)piperazine; tert-Butyl 4-(4-aminobenzoyl)piperazine-1-carboxylate; 4-(4-Aminobenzoyl)piperazine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(4-aminobenzoyl)piperazine; N-Boc-4-(4-aminobenzoyl)piperazine; 350684-49-0; 4-(4-Aminobenzoyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 4-(4-Aminobenzoyl)Tetrahydro-1(2H)-Pyrazinecarboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. All materials are subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.