Description

(R)-3-n-Benzyl-2-Ethyl Piperazine CAS NO 347195-55-5 is a high-purity chiral piperazine derivative, a critical building block in modern pharmaceutical synthesis. Its value lies in its role as a versatile intermediate for creating enantiomerically pure active pharmaceutical ingredients (APIs) and advanced fine chemicals. This compound is essential for research and development chemists and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel therapeutics with high stereoselectivity.

Application

• Key chiral intermediate in the synthesis of central nervous system (CNS) active pharmaceuticals, including potential antidepressants and antipsychotics.
• Building block for the development of protease inhibitors and other enzyme-targeted drugs.
• Precursor in the research and production of specialty agrochemicals requiring specific stereochemistry for enhanced activity.
• Versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Intermediate for custom synthesis and contract manufacturing of complex organic molecules.
• Starting material for catalyst ligands and chiral auxiliaries used in asymmetric synthesis.

Basic Information

Product Name	(R)-3-n-Benzyl-2-Ethyl Piperazine
CAS No.	347195-55-5
Molecular Formula	C13H20N2
Molecular Weight	204.31 g/mol
Synonyms	(R)-2-Ethyl-3-benzylpiperazine; (R)-3-Benzyl-2-ethylpiperazine; (2R)-2-Ethyl-3-(phenylmethyl)piperazine; (R)-2-Ethyl-3-(benzyl)piperazine; 1-Benzyl-2-ethyl-(R)-piperazine; (R)-1-Benzyl-2-ethylpiperazine; (R)-Benzyl Ethyl Piperazine
EINECS	Contact for details

Quality Control

Our (R)-3-n-Benzyl-2-Ethyl Piperazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to meet the exacting standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.