Description

1-Benzyl-3(R)-Ethyl-Piperazine-2,5-Dione is a chiral piperazinedione derivative, a sophisticated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its stereochemically defined structure, which is crucial for imparting specific biological activity and physical properties in target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the construction of complex molecules for novel pesticides and herbicides, where stereochemistry affects efficacy and environmental profile.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for developing novel chiral ligands and organocatalysts used in enantioselective synthesis.
• Peptidomimetic Research: Its constrained diketopiperazine scaffold is valuable for designing and synthesizing peptidomimetics to modulate protein-protein interactions.
• Chemical Biology Probe Development: Employed in the synthesis of specialized molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical intermediate for custom synthesis houses serving the life sciences sector with bespoke, high-purity compounds.

Basic Information

Product Name	1-Benzyl-3(R)-Ethyl-Piperazine-2,5-Dione
CAS No.	347195-54-4
Molecular Formula	C13H16N2O2
Molecular Weight	232.28 g/mol
Synonyms	(R)-1-Benzyl-3-ethylpiperazine-2,5-dione; 1-Benzyl-3-[(R)-ethyl]-2,5-piperazinedione; 3(R)-Ethyl-1-benzylpiperazine-2,5-dione; (R)-3-Ethyl-1-benzylpiperazine-2,5-dione; 2,5-Diketopiperazine, 1-benzyl-3-[(R)-ethyl]-; 1-Benzyl-3-(R)-ethyl-2,5-diketopiperazine; BEPD; (R)-Benzylethyl Diketopiperazine
EINECS	Contact for details

Quality Control

Our 1-Benzyl-3(R)-Ethyl-Piperazine-2,5-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.