Description

4-(3-(Methylsulfonyl)Phenyl)Piperidine is a high-purity, advanced pharmaceutical intermediate characterized by its piperidine core linked to a methylsulfonylphenyl moiety. This compound is of significant value in modern medicinal chemistry for constructing novel drug candidates, particularly in central nervous system (CNS) and oncology research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for synthesizing potent and selective small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates targeting various disease pathways.
• CNS Drug Research: Used in developing potential treatments for neurological disorders, leveraging the piperidine scaffold's bioactivity.
• Kinase Inhibitor Development: Serves as a core structure in the design and synthesis of protein kinase inhibitors for oncology applications.
• Chemical Biology & Proteomics: Employed as a molecular probe or tag in studying protein-ligand interactions and biological mechanisms.
• Process Chemistry & Scale-Up: Utilized in route scouting and optimization for the commercial-scale manufacturing of active pharmaceutical ingredients (APIs).
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects undertaken by CDMOs (Contract Development and Manufacturing Organizations).

Basic Information

Product Name	4-(3-(Methylsulfonyl)Phenyl)Piperidine
CAS No.	346688-72-0
Molecular Formula	C12H17NO2S
Molecular Weight	239.33 g/mol
Synonyms	4-(3-Methanesulfonylphenyl)piperidine; 3-(Piperidin-4-yl)phenyl methyl sulfone; 4-(3-Methylsulfonylphenyl)piperidine; 1-[3-(Methylsulfonyl)phenyl]-4-piperidine; 4-(3-Mesylphenyl)piperidine; 346688-72-0; 4-(3-Methanesulphonylphenyl)piperidine
EINECS	Contact for details

Quality Control

Every batch of 4-(3-(Methylsulfonyl)Phenyl)Piperidine is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard grade meets high-purity specifications suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), identity (IR, NMR), and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.