Description

6-(1-Methanesulfonyl-1-Methyl-Ethyl)-8-(3-[(E)-2-(4-Methanesulfonyl-Phenyl)-2-(3-Methyl-[1,2,4]Oxadiazol-5-Yl)-Vinyl]-Phenyl)-Quinoline is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure incorporating quinoline and oxadiazole moieties. This compound is of significant value for its role in the research and development of novel therapeutic agents, particularly in targeted drug discovery programs. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for synthesizing potential drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates for preclinical and clinical research.
• Kinase Inhibitor Research: Used in the development of potential kinase inhibitors due to the common presence of quinoline scaffolds in such compounds.
• Chemical Biology Probes: Serves as a core structure for creating specialized probes to study biological pathways and protein functions.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of lead molecules.
• Process Chemistry Development: Used for scaling up and optimizing synthetic routes for potential Active Pharmaceutical Ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global drug discovery pipelines.

Basic Information

Item	Details
Product Name	6-(1-Methanesulfonyl-1-Methyl-Ethyl)-8-(3-[(E)-2-(4-Methanesulfonyl-Phenyl)-2-(3-Methyl-[1,2,4]Oxadiazol-5-Yl)-Vinyl]-Phenyl)-Quinoline
CAS No.	346629-30-9
Molecular Formula	C31H29N3O5S2
Molecular Weight	587.71 g/mol
Synonyms	6-(1-Methanesulfonyl-1-methylethyl)-8-[3-[(E)-2-(4-methanesulfonylphenyl)-2-(3-methyl-1,2,4-oxadiazol-5-yl)ethenyl]phenyl]quinoline; 8-(3-((E)-2-(4-(Methylsulfonyl)phenyl)-2-(3-methyl-1,2,4-oxadiazol-5-yl)vinyl)phenyl)-6-(1-(methylsulfonyl)-1-methylethyl)quinoline; CAS 346629-30-9; Quinoline derivative, oxadiazole-containing; Sulfone-functionalized quinoline intermediate.
EINECS	Contact for details

Quality Control

Our 6-(1-Methanesulfonyl-1-Methyl-Ethyl)-8-(3-[(E)-2-(4-Methanesulfonyl-Phenyl)-2-(3-Methyl-[1,2,4]Oxadiazol-5-Yl)-Vinyl]-Phenyl)-Quinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Any single impurity ≤ 1.0%; Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.