Description

3,4-Piperidinediol,5-(Hydroxymethyl)-,(3S,4R,5R)-(9Ci) is a high-purity, stereochemically defined piperidine derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in its multifunctional structure, which provides multiple points for selective chemical modification, enabling the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active pharmaceutical ingredients (APIs) and fine chemicals where precise stereochemistry is paramount. The CAS number for this specific stereoisomer is 346408-24-0.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, including enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides with improved efficacy and environmental profiles.
• Asymmetric Catalysis: Serves as a precursor for chiral ligands or catalysts used in enantioselective synthesis.
• Chemical Biology & Proteomics: Employed as a scaffold or linker in the design of molecular probes and activity-based protein profiling (ABPP) reagents.
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	3,4-Piperidinediol,5-(Hydroxymethyl)-,(3S,4R,5R)-(9Ci)
CAS No.	346408-24-0
Molecular Formula	C6H13NO3
Molecular Weight	147.17 g/mol
Synonyms	(3S,4R,5R)-5-(Hydroxymethyl)piperidine-3,4-diol; (3S,4R,5R)-5-(Hydroxymethyl)-3,4-piperidinediol; 1-Deoxynojirimycin derivative; Dihydroxypiperidinemethanol; Azasugar intermediate; Chiral piperidine triol; (3S,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)piperidine
EINECS	Contact for details

Quality Control

Every batch of 3,4-Piperidinediol,5-(Hydroxymethyl)-,(3S,4R,5R)-(9Ci) is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure the identity, purity, and stereochemical integrity of the product meet the exacting standards required for research and cGMP manufacturing. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting results from advanced analytical techniques including chiral HPLC, NMR, and mass spectrometry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Optimal storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.