Description

5,6,7,8-Tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride is a heterocyclic organic compound that serves as a crucial building block in modern pharmaceutical research and development. Its fused triazolo-pyrazine structure makes it a valuable intermediate for synthesizing novel active pharmaceutical ingredients (APIs) with potential therapeutic applications. This high-purity compound is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the development of central nervous system (CNS) and other targeted therapies.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the research and development of new drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold or building block for constructing complex molecules in drug discovery programs.
• CNS Drug Development: Employed in the synthesis of compounds targeting neurological and psychiatric disorders.
• Chemical Biology Probes: Serves as a starting material for creating tool compounds to study biological pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Used in university and institutional labs for heterocyclic chemistry studies and novel methodology development.

Basic Information

Product Name	5,6,7,8-Tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride
CAS No.	345311-09-3
Molecular Formula	C6H10ClN5
Molecular Weight	187.63 g/mol
Synonyms	5,6,7,8-Tetrahydro-1,2,4-triazolo[4,3-a]pyrazine hydrochloride; 1,2,4-Triazolo[4,3-a]pyrazine, 5,6,7,8-tetrahydro-, hydrochloride; Tetrahydrotriazolopyrazine HCl; THTP hydrochloride; 345311-09-3; 5,6,7,8-Tetrahydro-[1,2,4]triazol[4,3-a]pyrazine HCl
EINECS	Contact for details

Quality Control

Our 5,6,7,8-Tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to industry-standard analytical methods, including HPLC, NMR, and mass spectrometry, to guarantee product integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.