Description

2-Amino-5-Bromo-3-Phenylpyrazine is a high-purity brominated pyrazine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular scaffold, which enables the construction of complex heterocyclic compounds with tailored properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its halogenated pyrazine core.
• Material Science: Building block for creating specialized organic ligands, dyes, or electronic materials.
• Chemical Synthesis: Versatile reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and further functionalization due to the reactive amino and bromo groups.
• Academic & R&D: Serves as a standard compound for methodological studies in organic chemistry and medicinal chemistry research.

Basic Information

Product Name	2-Amino-5-Bromo-3-Phenylpyrazine
CAS No.	344940-70-1
Molecular Formula	C10H8BrN3
Molecular Weight	250.10 g/mol
Synonyms	5-Bromo-3-phenylpyrazin-2-amine; 3-Phenyl-5-bromopyrazin-2-amine; 2-Amino-5-bromo-3-phenylpyrazine; 5-Bromo-2-amino-3-phenylpyrazine; 344940-70-1; 2-Pyrazinamine, 5-bromo-3-phenyl-
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Bromo-3-Phenylpyrazine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) with batch-specific data is provided to guarantee it meets the stringent requirements for research and commercial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.