Description

1-(1,3-Benzodioxol-5-Yl)-3-[4-(4-Fluorophenyl)Piperazino]-1-Propanone CAS NO 344569-55-7 is a high-purity synthetic organic compound featuring a benzodioxole and a fluorophenylpiperazine moiety. This specialized chemical serves as a critical advanced pharmaceutical intermediate or research-grade building block for the development of novel bioactive molecules. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential central nervous system (CNS) active agents, including antidepressants and anxiolytics.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Biochemical Tool Compound: Serves as a reference standard or ligand in pharmacological assays targeting serotonin and dopamine receptor systems.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of complex active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development services for the life sciences industry.

Basic Information

Product Name	1-(1,3-Benzodioxol-5-Yl)-3-[4-(4-Fluorophenyl)Piperazino]-1-Propanone
CAS No.	344569-55-7
Molecular Formula	C20H21FN2O3
Molecular Weight	356.40 g/mol
Synonyms	1-(1,3-Benzodioxol-5-yl)-3-[4-(4-fluorophenyl)piperazin-1-yl]propan-1-one; 3-[4-(4-Fluorophenyl)piperazin-1-yl]-1-(1,3-benzodioxol-5-yl)propan-1-one; 1-(Benzo[d][1,3]dioxol-5-yl)-3-(4-(4-fluorophenyl)piperazin-1-yl)propan-1-one; 344569-55-7; 1,3-Benzodioxole-5-propanone, 1-[4-(4-fluorophenyl)-1-piperazinyl]-; N-(4-Fluorophenyl)-N'-[3-(1,3-benzodioxol-5-yl)-3-oxopropyl]piperazine
EINECS	Contact for details

Quality Control

Our production of this compound adheres to stringent quality protocols suitable for research and development applications. Every batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided, detailing results from tests such as HPLC purity, NMR, and mass spectrometry. We support cGMP-compliant manufacturing upon request to meet the exacting standards of preclinical and clinical-stage pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.