Description

3-(2,5-Dimethoxyphenyl)-2-Propenoylchloride is a specialized organic intermediate featuring a reactive acid chloride group conjugated to a dimethoxyphenyl aromatic system. This compound matters for its role as a key building block in the synthesis of more complex molecules, particularly in pharmaceutical and advanced material research. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or possessing specific receptor binding profiles.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, or insecticides where the dimethoxyphenyl moiety imparts specific biological activity.
• Liquid Crystal & OLED Material Research: Serves as a building block for creating advanced organic electronic materials due to its planar, conjugated structure and functional handle for polymerization or derivatization.
• Polymer Chemistry: Can be incorporated as a monomer or cross-linking agent to introduce aromaticity and specific functionality into polymer backbones.
• Chemical Biology & Proteomics: Employed in the synthesis of activity-based probes or affinity tags for studying enzyme function and protein interactions.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploring new chemical spaces in synthetic organic chemistry.

Basic Information

Item	Detail
Product Name	3-(2,5-Dimethoxyphenyl)-2-Propenoylchloride
CAS No.	344402-16-0
Molecular Formula	C11H11ClO3
Molecular Weight	226.66 g/mol
Synonyms	3-(2,5-Dimethoxyphenyl)acryloyl chloride; (E)-3-(2,5-Dimethoxyphenyl)acryloyl chloride; 2,5-Dimethoxycinnamoyl chloride; (2E)-3-(2,5-Dimethoxyphenyl)prop-2-enoyl chloride; 344402-16-0; trans-3-(2,5-Dimethoxyphenyl)acryloyl chloride
EINECS	Contact for details

Quality Control

Our 3-(2,5-Dimethoxyphenyl)-2-Propenoylchloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and Karl Fischer titration for moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and moisture-sensitive nature, containers should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong bases, oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.