Description

2-Amino-3-Iodopyrazine is a versatile halogenated pyrazine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of both an amino group and an iodine atom on the pyrazine ring, enabling a wide range of cross-coupling and functionalization reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive heterocyclic core.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and organic electronic materials.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig amination.
• Ligand Synthesis: Utilized for constructing complex nitrogen-containing ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology: Acts as a probe or labeling reagent in bioconjugation chemistry and medicinal chemistry research.

Basic Information

Item	Details
Product Name	2-Amino-3-Iodopyrazine
CAS No.	344329-41-5
Molecular Formula	C4H4IN3
Molecular Weight	221.00 g/mol
Synonyms	3-Iodo-2-pyrazinamine; 3-Iodopyrazin-2-amine; 2-Pyrazinamine, 3-iodo-; 2-Amino-3-iodopyrazine; 3-Iodo-2-aminopyrazine
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Iodopyrazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.