Description

2-Chloro-6-Piperidin-1-Ylpyrazine is a high-purity heterocyclic organic compound featuring a pyrazine core substituted with chlorine and a piperidine group. This specific molecular architecture makes it a valuable and versatile chemical intermediate for advanced synthesis, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical and fine chemical sectors for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Catalyst Preparation: The nitrogen-rich pyrazine and piperidine moieties make it a potential precursor for chelating ligands or organocatalysts.
• Material Science Precursor: Can be utilized in the development of advanced organic materials, such as organic semiconductors or metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Chloro-6-Piperidin-1-Ylpyrazine
CAS No.	343856-62-2
Molecular Formula	C9H12ClN3
Molecular Weight	197.66 g/mol
Synonyms	2-Chloro-6-(1-piperidinyl)pyrazine; 2-Chloro-6-piperidin-1-ylpyrazine; 6-Chloro-3-piperidin-1-ylpyrazine; 2-Chloro-6-(piperidin-1-yl)pyrazine; Pyrazine, 2-chloro-6-(1-piperidinyl)-; 343856-62-2; 2-Chloro-6-piperidinopyrazine
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Piperidin-1-Ylpyrazine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and reliable supply for critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.