Description

Methyl 4-Amino-2-(4-Benzylpiperazino)-1,3-Thiazole-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a distinct thiazole-piperazine hybrid structure. This compound is critical for research and development in medicinal chemistry, particularly for synthesizing novel bioactive molecules targeting the central nervous system. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in neurological and psychiatric disorder research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the multi-step synthesis of potential APIs with thiazole and piperazine pharmacophores.
• Biochemical Tool Compound: Employed in vitro and in vivo studies to investigate specific biological pathways and receptor interactions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.

Basic Information

Product Name	Methyl 4-Amino-2-(4-Benzylpiperazino)-1,3-Thiazole-5-Carboxylate
CAS No.	343375-51-9
Molecular Formula	C16H21N5O2S
Molecular Weight	347.44 g/mol
Synonyms	4-Amino-2-(4-benzylpiperazin-1-yl)-1,3-thiazole-5-carboxylic acid methyl ester; Methyl 4-amino-2-(4-benzyl-1-piperazinyl)-5-thiazolecarboxylate; 343375-51-9; 2-(4-Benzylpiperazino)-4-amino-5-methoxycarbonylthiazole; 5-Methoxycarbonyl-4-amino-2-(4-benzylpiperazino)thiazole
EINECS	Contact for details

Quality Control

Our production of Methyl 4-Amino-2-(4-Benzylpiperazino)-1,3-Thiazole-5-Carboxylate adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Quality is verified against established internal specifications using advanced analytical techniques. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.