Description

4-(3-Formyl-4-Hydroxyphenyl)Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-value pharmaceutical intermediate and chemical building block characterized by its multifunctional piperazine and phenolic aldehyde structure. This compound is critical for research and development in medicinal chemistry, particularly for its role in constructing complex molecular architectures. It is primarily sought by pharmaceutical manufacturers and R&D laboratories engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in the design and development of new chemical entities (NCEs) and lead optimization studies.
• API Synthesis: Serves as a precursor in the multi-step synthesis of final active pharmaceutical ingredients.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological pathways and target engagement.
• Fine Chemical Production: Employed in the manufacture of specialty and custom fine chemicals for advanced applications.
• Academic & Industrial R&D: Essential reagent for synthetic organic chemistry research in both academic and corporate settings.

Basic Information

Product Name	4-(3-Formyl-4-Hydroxyphenyl)Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	343306-50-3
Molecular Formula	C16H22N2O4
Molecular Weight	306.36 g/mol
Synonyms	tert-Butyl 4-(3-formyl-4-hydroxyphenyl)piperazine-1-carboxylate; 1-Boc-4-(3-formyl-4-hydroxyphenyl)piperazine; 4-(3-Formyl-4-hydroxyphenyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; 4-(3-Formyl-4-hydroxyphenyl)piperazine-1-carboxylic acid tert-butyl ester; 4-(3-Formyl-4-hydroxyphenyl)piperazine-1-carboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-4-(3-formyl-4-hydroxyphenyl)piperazine; Boc-4-(3-formyl-4-hydroxyphenyl)piperazine
EINECS	Contact for details

Quality Control

Our 4-(3-Formyl-4-Hydroxyphenyl)Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its sensitivity to oxidation, the container should be sealed immediately after use to minimize exposure to air.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.