Description

Piperazine, 1-(2,2-Dimethylpropyl)-4-Methyl- (9Ci) is a specialized piperazine derivative with a branched alkyl substituent, offering unique steric and electronic properties for advanced chemical synthesis. This compound serves as a crucial high-value intermediate in the development of active pharmaceutical ingredients (APIs) and fine chemicals, where its specific structure enables precise molecular modifications. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging its piperazine core for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Intermediate for manufacturing dyes, pigments, and other performance chemicals requiring specific amine functionality.
• Polymer Modification: Employed to introduce amine groups into polymer chains, altering material properties like adhesion, solubility, and reactivity.
• Academic and Industrial Research: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry research programs.

Basic Information

Item	Details
Product Name	Piperazine, 1-(2,2-Dimethylpropyl)-4-Methyl- (9Ci)
CAS No.	343271-73-8
Molecular Formula	C10H22N2
Molecular Weight	170.30 g/mol
Synonyms	1-Neopentyl-4-methylpiperazine; 4-Methyl-1-neopentylpiperazine; 1-(2,2-Dimethylpropyl)-4-methylpiperazine; 1-(Neopentyl)-4-methylpiperazine; Neopentyl 4-methylpiperazine; N-Neopentyl-N'-methylpiperazine
EINECS	Contact for details

Quality Control

Every batch of Piperazine, 1-(2,2-Dimethylpropyl)-4-Methyl- (9Ci) is produced under a strict quality management system. We provide comprehensive Certificates of Analysis (COA) that detail purity, identity, and impurity profiles, ensuring traceability and consistency for your critical R&D and scale-up processes. Our quality commitment aligns with cGMP principles where applicable, supporting regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.