Description

2,5-Piperazinedione, 3-(Hydroxymethyl)-6-Methyl-, (6S)- (9Ci) is a high-purity chiral piperazinedione derivative, a key structural motif and advanced intermediate in modern organic synthesis. Its value lies in its stereochemically defined core, which is critical for constructing complex molecules with high enantiomeric purity. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly for the synthesis of novel active pharmaceutical ingredients (APIs), peptidomimetics, and specialized catalysts.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral building block for the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Peptidomimetics Research: Used in the design and development of peptidomimetic compounds, which mimic peptides but offer improved metabolic stability and bioavailability.
• Asymmetric Synthesis: Acts as a chiral auxiliary or precursor for ligands in asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Chemical Biology Probes: Employed in the creation of specialized molecular probes for studying enzyme mechanisms and protein-protein interactions.
• Fine Chemical Synthesis: A versatile intermediate for the multi-step synthesis of complex, high-value specialty chemicals and natural product analogs.
• Academic & Industrial R&D: A valuable reagent for method development and exploratory chemistry in both university laboratories and corporate R&D centers.

Basic Information

Product Name	2,5-Piperazinedione, 3-(Hydroxymethyl)-6-Methyl-, (6S)- (9Ci)
CAS No.	342416-68-6
Molecular Formula	C7H12N2O3
Molecular Weight	172.18 g/mol
Synonyms	(6S)-3-(Hydroxymethyl)-6-methylpiperazine-2,5-dione; (3S,6S)-3-(Hydroxymethyl)-6-methylpiperazine-2,5-dione; L-3-Hydroxymethyl-6-methyl-2,5-piperazinedione; (S)-3-(Hydroxymethyl)-6-methylpiperazine-2,5-dione; A chiral dioxopiperazine derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of our 2,5-Piperazinedione, 3-(Hydroxymethyl)-6-Methyl-, (6S)- (9Ci) is manufactured under strict quality management systems. We employ advanced analytical techniques, including chiral HPLC and NMR, to ensure high enantiomeric purity and chemical identity. Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.