Description

3-(1H-Imidazol-1-Yl)-Pyrazinecarbonitrile is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical and agrochemical agents, particularly those targeting specific enzymatic pathways. Pharmaceutical R&D laboratories and fine chemical manufacturers need it for constructing complex molecular architectures, leveraging its unique imidazole-pyrazine hybrid structure to impart specific biological activity.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and insecticides with novel modes of action.
• Ligand Synthesis: Serves as a versatile scaffold for creating complex ligands in coordination chemistry and catalysis.
• Material Science: Investigated as a building block for organic electronic materials and metal-organic frameworks (MOFs).
• Bioconjugation Chemistry: Utilized in the design of probes and linkers for biochemical and diagnostic applications.

Basic Information

Product Name	3-(1H-Imidazol-1-Yl)-Pyrazinecarbonitrile
CAS No.	342412-44-6
Molecular Formula	C8H5N5
Molecular Weight	171.16 g/mol
Synonyms	3-(1H-Imidazol-1-yl)pyrazine-2-carbonitrile; 3-(Imidazol-1-yl)pyrazinecarbonitrile; 2-Cyano-3-(1H-imidazol-1-yl)pyrazine; Pyrazinecarbonitrile, 3-(1H-imidazol-1-yl)-; 342412-44-6; 3-(1H-Imidazol-1-yl)pyrazine-2-carbonitrile; 3-(Imidazol-1-Yl)-2-Pyrazinecarbonitrile
EINECS	Contact for details

Quality Control

Our 3-(1H-Imidazol-1-Yl)-Pyrazinecarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.