Description

Sipoglitazar CAS NO 342026-92-0 is a potent and selective dual peroxisome proliferator-activated receptor (PPAR) alpha/gamma agonist. This compound is of significant interest in pharmaceutical research and development, primarily for its potential in modulating lipid and glucose metabolism. It is a critical intermediate or active pharmaceutical ingredient (API) for researchers and manufacturers targeting metabolic disorders such as type 2 diabetes and dyslipidemia.

Application

• Pharmaceutical Research: Primary use as a reference standard or active compound in metabolic disease research, particularly for studying PPAR-mediated pathways.
• Drug Development: Serves as a key intermediate or the core API in the synthesis of investigational new drugs targeting diabetes and related syndromes.
• Biochemical Assays: Utilized in in vitro and in vivo studies to evaluate efficacy, pharmacokinetics, and mechanism of action of PPAR agonists.
• Academic Research: Used in university and institutional labs for fundamental research into nuclear receptor biology and metabolic regulation.
• Preclinical Studies: Essential for conducting animal model studies to assess therapeutic potential and safety profiles.
• Analytical Standard: Employed as a high-purity standard for method development and quality control (HPLC, LC-MS) in analytical laboratories.

Basic Information

Product Name	Sipoglitazar
CAS No.	342026-92-0
Molecular Formula	C₂₄H₂₀O₅S
Molecular Weight	420.48 g/mol
Synonyms	TAK-559; Sipoglitazar; 5-[[4-[3-(4-Ethoxyphenyl)propoxy]phenyl]methyl]-2,4-thiazolidinedione; 5-[[4-[3-(p-Ethoxyphenyl)propoxy]phenyl]methyl]thiazolidine-2,4-dione; PPAR α/γ Agonist TAK-559; UNII-4Q6K5S5A0F
EINECS	Contact for details

Quality Control

Our Sipoglitazar is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and MS, and stringent control of residual solvents and impurities to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccants or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.