Description

[1,4']Bipiperidinyl-3-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its unique bipiperidinyl scaffold. This compound is of significant commercial interest for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of central nervous system (CNS) and other therapeutic agents, where its specific structure enables key molecular interactions.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, particularly those targeting neurological receptors.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic molecules.
• Chemical Synthesis Building Block: Provides a versatile bipiperidine core for constructing diverse chemical libraries for high-throughput screening.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for cGMP production of clinical trial materials.
• Academic Research: Employed in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	[1,4']Bipiperidinyl-3-Carboxylic Acid Ethyl Ester
CAS No.	340962-71-2
Molecular Formula	C13H22N2O2
Molecular Weight	238.33 g/mol
Synonyms	Ethyl 1,4'-Bipiperidine-3-carboxylate; 3-Carbethoxy-1,4'-bipiperidine; 1,4'-Bipiperidine-3-carboxylic Acid Ethyl Ester; 3-(Ethoxycarbonyl)-1,4'-bipiperidine; 1,4'-Bipiperidinyl-3-carboxylic Acid Ethyl Ester; 3-Carbethoxy-4-piperidinopiperidine; Ethyl 3-(1,4'-Bipiperidinyl)carboxylate
EINECS	Contact for details

Quality Control

Our [1,4']Bipiperidinyl-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of moisture from the atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.