Description

Di-tert-Butyl Piperazine-1,2-Dicarboxylate is a high-purity, protected piperazine derivative serving as a critical building block in advanced organic synthesis. Its primary value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs). This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for their synthetic workflows.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those containing piperazine or morpholine cores, such as kinase inhibitors, antivirals, and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the piperazine moiety imparts specific biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer Chemistry: Acts as a monomer or chain extender in the production of specialty polyamides, polyurethanes, and other performance polymers.
• Chemical Research & Development: A versatile building block for constructing diverse heterocyclic compounds and exploring new chemical spaces in medicinal chemistry programs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules at various scales.

Basic Information

Product Name	Di-tert-Butyl Piperazine-1,2-Dicarboxylate
CAS No.	340256-13-5
Molecular Formula	C14H26N2O4
Molecular Weight	286.37 g/mol
Synonyms	1,2-Piperazinedicarboxylic acid, 1,4-di-tert-butyl ester; Di-tert-butyl 1,2-piperazinedicarboxylate; 1,4-Di-Boc-piperazine-2-carboxylic acid; 1-Boc-4-(Boc-amino)piperazine-2-carboxylic acid; (2S)-1,4-Di-tert-butyl 2-piperazinecarboxylate (for enantiopure forms); 1,4-Di-Boc-piperazine; Boc-Pip(Boc)-OH; DBPC
EINECS	Contact for details

Quality Control

Our Di-tert-Butyl Piperazine-1,2-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure it meets the stringent requirements of our global customer base. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be hygroscopic; ensure containers are sealed after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.