Description

1,3-Piperidinedicarboxylic Acid, 3-(Phenylmethyl)-, 1-(1,1-Dimethylethyl) Ester, (3R)- is a high-purity, chiral piperidine derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate complex, stereodefined piperidine motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and metabolic disorder targets.
• Asymmetric Synthesis: Employed as a sophisticated building block for constructing complex, enantiomerically pure molecules in medicinal chemistry and process development.
• Agrochemical Research: Used in the synthesis of novel chiral compounds with potential biological activity for crop protection applications.
• Catalyst and Ligand Development: Serves as a precursor for the synthesis of novel chiral catalysts and ligands used in asymmetric transformations.
• Academic & Industrial R&D: A valuable reagent for chemical libraries and exploratory research in synthetic organic chemistry.

Basic Information

Product Name	1,3-Piperidinedicarboxylic Acid, 3-(Phenylmethyl)-, 1-(1,1-Dimethylethyl) Ester, (3R)-
CAS No.	339539-81-0
Molecular Formula	C19H27NO4
Molecular Weight	333.43 g/mol
Synonyms	(3R)-3-Benzyl-1-(tert-butyl) piperidine-1,3-dicarboxylate; 1-tert-Butyl 3-methyl (3R)-3-benzylpiperidine-1,3-dicarboxylate; (R)-1-Boc-3-benzylpiperidine-3-carboxylic acid; (3R)-1-(tert-Butoxycarbonyl)-3-(phenylmethyl)piperidine-3-carboxylic acid; tert-Butyl (3R)-3-(benzyl)-3-(methoxycarbonyl)piperidine-1-carboxylate; (R)-3-Benzyl-1-Boc-piperidine-3-carboxylic acid methyl ester; 339539-81-0; (R)-1-N-Boc-3-benzyl-3-piperidinecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 1,3-Piperidinedicarboxylic Acid, 3-(Phenylmethyl)-, 1-(1,1-Dimethylethyl) Ester, (3R)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and advanced synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.