Description

2-Piperidinecarboxylicacid,4-Methyl-,Methylester,(2R,4R)-Rel-(9Ci) is a high-purity, stereochemically defined chiral piperidine derivative. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile chiral building block for the synthesis of complex bioactive molecules. It is essential for research and development in the pharmaceutical industry, particularly for creating novel therapeutics where specific stereochemistry is paramount for efficacy and safety. The product, identified by CAS number 339183-93-6, is supplied under stringent quality control to meet the exacting demands of modern organic synthesis.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and cardiovascular drugs.
• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce high enantioselectivity.
• Medicinal Chemistry Research: Used in drug discovery programs for structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Development: Building block for creating chiral pesticides and herbicides with improved selectivity and environmental profile.
• Fine Chemical Synthesis: Intermediate in the production of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & Industrial R&D: Serves as a reference standard and starting material in chemical research focused on alkaloid chemistry and heterocyclic compounds.

Basic Information

Product Name	2-Piperidinecarboxylicacid,4-Methyl-,Methylester,(2R,4R)-Rel-(9Ci)
CAS No.	339183-93-6
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	(2R,4R)-4-Methylpipecolic Acid Methyl Ester; Methyl (2R,4R)-4-Methylpipecolate; (2R,4R)-4-Methyl-2-piperidinecarboxylic Acid Methyl Ester; rel-(2R,4R)-Methyl 4-methylpipecolate; 4-Methyl-DL-pipecolic Acid Methyl Ester (stereoisomer); Chiral Piperidine Ester; Methyl 4-Methylpipecolate
EINECS	Contact for details

Quality Control

Our 2-Piperidinecarboxylicacid,4-Methyl-,Methylester,(2R,4R)-Rel-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We adhere to relevant cGMP guidelines for the production of advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (diastereomeric excess)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.