Description

3-((4-[2,6-Dinitro-4-(Trifluoromethyl)Phenyl]Piperazino)Methylene)-2-Benzofuran-1(3H)-One is a high-purity, complex heterocyclic compound featuring a benzofuranone core linked to a substituted piperazine and a trifluoromethylphenyl group. This molecular architecture makes it a valuable advanced pharmaceutical intermediate and a key building block for research into novel bioactive molecules. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis sectors for developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its nitro and trifluoromethyl functional groups.
• Chemical Biology Probe: Acts as a scaffold or ligand in the design of molecular probes for studying enzyme inhibition and receptor binding.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with unique optical or electronic properties.
• Organic Synthesis Building Block: Employed in multi-step synthetic routes to construct more complex polycyclic or heterocyclic structures.

Basic Information

Product Name	3-((4-[2,6-Dinitro-4-(Trifluoromethyl)Phenyl]Piperazino)Methylene)-2-Benzofuran-1(3H)-One
CAS No.	338976-29-7
Molecular Formula	C20H15F3N4O5
Molecular Weight	448.35 g/mol
Synonyms	3-[(4-{2,6-Dinitro-4-[(trifluoromethyl)phenyl]}piperazino)methylene]-1(3H)-isobenzofuranone; 3-((4-(2,6-Dinitro-4-(trifluoromethyl)phenyl)piperazin-1-yl)methylene)isobenzofuran-1(3H)-one; 3-[(4-{2,6-Dinitro-4-[(trifluoromethyl)phenyl]}piperazino)methylene]phthalide; CAS 338976-29-7; 3-((4-(2,6-Dinitro-4-(trifluoromethyl)phenyl)piperazin-1-yl)methylene)phthalide; 1(3H)-Isobenzofuranone, 3-[(4-[2,6-dinitro-4-(trifluoromethyl)phenyl]-1-piperazinyl)methylene]-
EINECS	Contact for details

Quality Control

Our production of 3-((4-[2,6-Dinitro-4-(Trifluoromethyl)Phenyl]Piperazino)Methylene)-2-Benzofuran-1(3H)-One adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support cGMP and ISO compliant manufacturing for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from heat, sparks, and open flame. For long-term storage, consider packaging under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.