Description

3-Amino-n-(4-Chlorophenyl)-2-Cyano-3-[4-(4-Methoxyphenyl)Piperazino]-2-Propenethioamide is a sophisticated organic building block featuring a unique piperazine-thioamide scaffold. This compound matters as a key synthetic intermediate for the development of novel pharmacologically active molecules, particularly in medicinal chemistry research. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers focused on creating new chemical entities (NCEs) for therapeutic applications.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening (HTS) in drug discovery programs.
• Chemical Biology Probes: Acts as a starting material for developing specific enzyme inhibitors or receptor modulators used as research tools.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for producing specialized, high-value organic compounds.

Basic Information

Item	Details
Product Name	3-Amino-n-(4-Chlorophenyl)-2-Cyano-3-[4-(4-Methoxyphenyl)Piperazino]-2-Propenethioamide
CAS No.	338966-42-0
Molecular Formula	C21H22ClN5OS
Molecular Weight	427.95 g/mol
Synonyms	3-Amino-N-(4-chlorophenyl)-2-cyano-3-[4-(4-methoxyphenyl)piperazin-1-yl]prop-2-enethioamide; 1-[4-(4-Methoxyphenyl)piperazin-1-yl]-3-amino-2-cyano-3-(4-chlorophenyl)prop-2-ene-1-thione; CAS 338966-42-0; 3-Amino-2-cyano-3-(4-chlorophenyl)-N-[4-(4-methoxyphenyl)piperazin-1-yl]prop-2-enethioamide
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry to verify identity and purity. Certificates of Analysis (COA) are available upon request, detailing batch-specific results for all critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.