Description

4-([3-(Trifluoromethyl)-2-Quinoxalinyl]Oxy)Benzenecarbonitrile is a high-value, specialized organic compound featuring a quinoxaline core functionalized with a trifluoromethyl group and a benzonitrile moiety. This molecular architecture makes it a critical advanced intermediate for research and development in demanding chemical synthesis. It is primarily sought by pharmaceutical and agrochemical R&D teams for constructing novel active ingredients, particularly where the trifluoromethyl group is leveraged to modulate bioavailability and metabolic stability.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in developing next-generation herbicides, fungicides, and insecticides, where the quinoxaline scaffold contributes to biological activity.
• Material Science Precursor: Serves as a specialized monomer or additive in the development of advanced polymers and functional materials with specific electronic or optical properties.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories for constructing complex heterocyclic systems and in methodology development.
• Ligand and Catalyst Development: The nitrogen-rich structure makes it a candidate for designing novel ligands in coordination chemistry and catalysis.

Basic Information

Product Name	4-([3-(Trifluoromethyl)-2-Quinoxalinyl]Oxy)Benzenecarbonitrile
CAS No.	338773-68-5
Molecular Formula	C₁₆H₈F₃N₃O
Molecular Weight	315.25 g/mol
Synonyms	4-[(3-Trifluoromethylquinoxalin-2-yl)oxy]benzonitrile; 2-(4-Cyanophenoxy)-3-(trifluoromethyl)quinoxaline; Benzonitrile, 4-[[3-(trifluoromethyl)-2-quinoxalinyl]oxy]-; 338773-68-5; 4-((3-(Trifluoromethyl)quinoxalin-2-yl)oxy)benzonitrile
EINECS	Contact for details

Quality Control

Our production of 4-([3-(Trifluoromethyl)-2-Quinoxalinyl]Oxy)Benzenecarbonitrile adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and physical properties are provided and available upon request, supporting your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.