Description

4-(4-Bromo-2-Fluorobenzyl)Morpholine is a high-value, synthetically versatile organic building block characterized by its morpholine and halogenated benzyl structure. This compound matters for its crucial role as an advanced intermediate in modern pharmaceutical and agrochemical research, enabling the construction of complex molecules with targeted biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, oncology, and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated aromatic system.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functional polymers and advanced organic materials where the morpholine moiety can impart specific solubility or binding properties.
• Chemical Biology Probes: Useful for constructing molecular probes and tags for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	4-(4-Bromo-2-Fluorobenzyl)Morpholine
CAS No.	338454-98-1
Molecular Formula	C11H13BrFNO
Molecular Weight	274.13 g/mol
Synonyms	4-[(4-Bromo-2-fluorophenyl)methyl]morpholine; Morpholine, 4-[(4-bromo-2-fluorophenyl)methyl]-; 4-(4-Bromo-2-fluorobenzyl)morpholine; 4-(4-Bromo-2-fluoro-benzyl)-morpholine; 338454-98-1; 4-(4-Bromo-2-fluorophenylmethyl)morpholine
EINECS	Contact for details

Quality Control

Our production of 4-(4-Bromo-2-Fluorobenzyl)Morpholine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (GC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.