Description

(S)-3-(4-Fluoro-2-Methylphenyl)Piperazin-2-One CAS NO 334477-18-8 is a high-purity chiral piperazinone derivative, a key advanced pharmaceutical intermediate (API) and building block in modern organic synthesis. Its value lies in its defined stereochemistry and functionalized aromatic-piperazinone core, which is critical for developing bioactive molecules with targeted pharmacological profiles. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries, particularly for creating novel drug candidates in central nervous system (CNS) and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in CNS-targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Agrochemical Synthesis: Serves as a precursor in the development of new pesticides and herbicides with specific chiral activity.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals.
• Ligand and Catalyst Development: Potential use in creating chiral ligands for asymmetric catalysis.
• Academic & Institutional R&D: A valuable reagent for methodological development and biochemical research in universities and contract research organizations (CROs).

Basic Information

Product Name	(S)-3-(4-Fluoro-2-Methylphenyl)Piperazin-2-One
CAS No.	334477-18-8
Molecular Formula	C11H13FN2O
Molecular Weight	208.23 g/mol
Synonyms	(S)-3-(4-Fluoro-2-methylphenyl)piperazin-2-one; (S)-3-(4-Fluoro-o-tolyl)piperazin-2-one; (2S)-3-(4-Fluoro-2-methylphenyl)-2-piperazinone; (S)-3-(4-Fluoro-2-methylphenyl)-2-piperazinone; 334477-18-8; (S)-enantiomer of 3-(4-Fluoro-2-methylphenyl)piperazin-2-one; (S)-FPMP; Chiral Fluoro-methylphenyl Piperazinone
EINECS	Contact for details

Quality Control

Our (S)-3-(4-Fluoro-2-Methylphenyl)Piperazin-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess), chemical purity (HPLC), and identity confirmation (NMR, IR, MS) to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with full analytical data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.