Description

1-(4-Pyridinylmethyl)-Piperazine 3Hcl is a high-purity organic salt derivative of piperazine, widely utilized as a critical pharmaceutical intermediate and a versatile building block in organic synthesis. Its molecular structure, featuring both pyridine and piperazine moieties, makes it a valuable precursor for the development of active pharmaceutical ingredients (APIs) and fine chemicals. This compound is essential for research and manufacturing in the pharmaceutical, agrochemical, and specialty chemical industries, where precise chemical functionality is required.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Ligand Synthesis: Used in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Agrochemical Research: Serves as a precursor in the development of new pesticides and herbicides.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new organic reactions and synthesizing complex molecules.
• Fine Chemical Production: Integral to the manufacture of specialty chemicals requiring specific nitrogen-containing heterocycles.

Basic Information

Product Name	1-(4-Pyridinylmethyl)-Piperazine 3Hcl
CAS No.	333992-80-6
Molecular Formula	C10H18Cl3N3
Molecular Weight	294.63 g/mol
Synonyms	1-[(Pyridin-4-yl)methyl]piperazine trihydrochloride; 1-(4-Pyridylmethyl)piperazine trihydrochloride; 4-[(Piperazin-1-yl)methyl]pyridine trihydrochloride; 1-(Pyridin-4-ylmethyl)piperazine hydrochloride (1:3); Piperazine, 1-[(4-pyridinyl)methyl]-, trihydrochloride
EINECS	Contact for details

Quality Control

Our 1-(4-Pyridinylmethyl)-Piperazine 3Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by FT-IR and NMR, and tests for residual solvents and heavy metals, to ensure it meets the stringent requirements for pharmaceutical intermediates. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.