Description

Ethyl 4-(2,3-Dihydro-1,4-Benzodioxin-6-Ylsulfonyl)-1-Piperazinecarboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its unique sulfonyl-piperazine-carboxylate structure. This compound is of significant commercial importance for its role in the synthesis of novel active pharmaceutical ingredients (APIs) targeting central nervous system and cardiovascular disorders. It is primarily required by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development.

Application

• Key Intermediate in API Synthesis: Serves as a critical building block for the development of new chemical entities, particularly in medicinal chemistry programs.
• Pharmacological Research: Used in the study and development of compounds with potential activity on serotonin, dopamine, or adrenergic receptors due to its structural motifs.
• Process Chemistry & Scale-Up: Employed in route scouting, optimization, and pilot-scale production for new drug candidates.
• Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in pharmaceutical manufacturing.
• Custom Synthesis: A starting material for the preparation of more complex, tailored molecules for client-specific research projects.

Basic Information

Product Name	Ethyl 4-(2,3-Dihydro-1,4-Benzodioxin-6-Ylsulfonyl)-1-Piperazinecarboxylate
CAS No.	333441-41-1
Molecular Formula	C15H20N2O6S
Molecular Weight	356.40 g/mol
Synonyms	Ethyl 4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)piperazine-1-carboxylate; 1,4-Benzodioxin-6-sulfonamide, N-(1-ethoxycarbonyl-4-piperazinyl)-, 2,3-dihydro-; 6-[(4-Ethoxycarbonyl-1-piperazinyl)sulfonyl]-2,3-dihydro-1,4-benzodioxine; 333441-41-1; Ethyl 4-(1,4-benzodioxan-6-ylsulfonyl)piperazine-1-carboxylate; Piperazine-1-carboxylic acid, 4-[(2,3-dihydro-1,4-benzodioxin-6-yl)sulfonyl]-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 4-(2,3-Dihydro-1,4-Benzodioxin-6-Ylsulfonyl)-1-Piperazinecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.