Description

2-Bromo-6-(3-Hydroxypyrrolidin-1-Yl)Pyridine is a versatile heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its bifunctional structure, incorporating both a reactive bromopyridine moiety and a chiral hydroxypyrrolidine group, making it a critical intermediate for constructing complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets, kinase inhibitors, and other biologically active molecules.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold.
• Ligand Synthesis: Serves as a starting material for creating chiral ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A valuable building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic Research: Utilized in university and institutional labs for methodological development in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	2-Bromo-6-(3-Hydroxypyrrolidin-1-Yl)Pyridine
CAS No.	332135-62-3
Molecular Formula	C9H11BrN2O
Molecular Weight	243.10 g/mol
Synonyms	1-(6-Bromopyridin-2-yl)-3-hydroxypyrrolidine; 3-Hydroxy-1-(6-bromo-2-pyridinyl)pyrrolidine; 2-Bromo-6-(3-hydroxy-1-pyrrolidinyl)pyridine; 6-Bromo-2-(3-hydroxypyrrolidin-1-yl)pyridine; Pyrrolidine, 1-(6-bromo-2-pyridinyl)-3-hydroxy-; 2-Bromo-6-(3-hydroxypyrrolidin-1-yl)pyridine; 1-(6-Bromo-2-pyridyl)-3-hydroxypyrrolidine
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-(3-Hydroxypyrrolidin-1-Yl)Pyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.