Description

Peliglitazar is a potent and selective dual peroxisome proliferator-activated receptor (PPAR) α/γ agonist. This compound is a high-purity pharmaceutical intermediate of significant interest for research and development in metabolic disorders. It is primarily utilized by pharmaceutical companies and research institutions focused on developing novel therapeutics for type 2 diabetes, dyslipidemia, and related conditions. Peliglitazar CAS NO 331744-64-0 represents a critical building block for advancing drug discovery programs in these therapeutic areas.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the research and development of novel PPAR agonist drugs.
• Metabolic Disease Research: Used as a reference standard and active compound in preclinical studies targeting type 2 diabetes and insulin resistance.
• Lipid Metabolism Studies: Employed in biochemical research to investigate mechanisms of dyslipidemia and fatty acid metabolism.
• Drug Discovery & Development: Serves as a core scaffold for structure-activity relationship (SAR) studies and medicinal chemistry optimization.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related pharmaceutical products.
• Academic & Institutional Research: A vital tool for universities and research institutes studying nuclear receptor pharmacology and metabolic syndrome pathways.

Basic Information

Product Name	Peliglitazar
CAS No.	331744-64-0
Molecular Formula	C₁₉H₂₀F₃NO₄
Molecular Weight	383.36 g/mol
Synonyms	Peliglitazar; (S)-2-Ethoxy-3-[4-[2-(4-methanesulfonyloxyphenyl)ethoxy]phenyl]propanoic acid; DRF 11605; DRF-11605; GQ-16; (αS)-2-Ethoxy-3-[4-[2-[4-[(methylsulfonyl)oxy]phenyl]ethoxy]phenyl]propanoic Acid; (S)-2-Ethoxy-3-(4-{2-[4-(methylsulfonyloxy)phenyl]ethoxy}phenyl)propionic acid
EINECS	Contact for details

Quality Control

Our Peliglitazar is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral purity verification, and identification by spectroscopic methods, to ensure it meets high-grade standards suitable for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformity to specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.