Description

n-Boc-Peg6-Alcohol CAS NO 331242-61-6 is a high-purity, heterobifunctional polyethylene glycol (PEG) derivative featuring a tert-butoxycarbonyl (Boc) protecting group on one terminus and a hydroxyl group on the other. This compound is a critical building block in pharmaceutical development and bioconjugation, enabling the precise synthesis of complex molecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for creating drug delivery systems, peptide modifications, and functionalized polymers.

Application

• Pharmaceutical Linker Synthesis: Serves as a versatile spacer or linker in the development of antibody-drug conjugates (ADCs), prodrugs, and targeted therapeutics.
• Peptide & Protein Modification: Used for PEGylation to enhance the solubility, stability, and pharmacokinetic profiles of peptides and proteins.
• Polymer Chemistry: Acts as a key monomer or initiator for synthesizing functionalized PEG-based copolymers and hydrogels with controlled properties.
• Protecting Group Strategy: The acid-labile Boc group allows for orthogonal deprotection in multi-step organic synthesis, facilitating complex molecule assembly.
• Bioconjugation & Labeling: Enables the attachment of dyes, probes, or other functional molecules to biomolecules via the reactive hydroxyl group.
• Material Science: Used to create surface coatings and modify materials to improve biocompatibility and introduce specific functional groups.

Basic Information

Product Name	n-Boc-Peg6-Alcohol
CAS No.	331242-61-6
Molecular Formula	C23H47NO9
Molecular Weight	481.62 g/mol
Synonyms	1-Boc-amino-3,6,9,12,15,18-hexaoxahenicosan-21-ol; 2-{2-[2-(2-{2-[2-(2-{[(tert-Butoxy)carbonyl]amino}ethoxy)ethoxy]ethoxy}ethoxy)ethoxy]ethoxy}ethanol; Boc-NH-PEG6-OH; Boc-Amino-PEG6-Alcohol; tert-Butyl (19-hydroxy-3,6,9,12,15,18-hexaoxa-2-azahenicosyl)carbamate; α-Boc-amino-ω-hydroxy-hexaethylene glycol; Boc-PEG6-OH
EINECS	Contact for details

Quality Control

Our n-Boc-Peg6-Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your research and cGMP-compliant workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.