Description

3-Oxa-6-Azatricyclo[3.2.1.02,4]Octan-7-One,(1S,2R,4S,5R)-(9Ci) is a high-purity, stereochemically defined bicyclic lactam compound, serving as a critical advanced pharmaceutical intermediate (API). Its unique bridged heterocyclic structure makes it a valuable chiral building block for the synthesis of complex, biologically active molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for constructing novel scaffolds in drug discovery programs targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in neurological and psychiatric therapeutic areas.
• Agrochemical Research: Used as a building block for developing new active ingredients with specific stereochemical requirements.
• Asymmetric Synthesis: Employed in catalytic and stoichiometric asymmetric reactions to introduce complex, rigid molecular architectures.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Chemical Biology: Utilized in the design and synthesis of molecular probes and enzyme inhibitors.
• Process Chemistry Development: Investigated for scalable synthetic routes in the production of high-value fine chemicals.

Basic Information

Item	Details
Product Name	3-Oxa-6-Azatricyclo[3.2.1.02,4]Octan-7-One,(1S,2R,4S,5R)-(9Ci)
CAS No.	329910-40-9
Molecular Formula	C6H7NO2
Molecular Weight	125.13 g/mol
Synonyms	(1S,2R,4S,5R)-3-Oxa-6-azatricyclo[3.2.1.02,4]octan-7-one; (1S,2R,4S,5R)-3-Oxa-6-azatricyclo[3.2.1.0²,⁴]octan-7-one; 3-Oxa-6-azatricyclo[3.2.1.02,4]octan-7-one, (1S,2R,4S,5R)-; (-)-3-Oxa-6-azatricyclo[3.2.1.02,4]octan-7-one; Bicyclic Lactam Derivative; 329910-40-9 (CAS)
EINECS	Contact for details

Quality Control

Our 3-Oxa-6-Azatricyclo[3.2.1.02,4]Octan-7-One,(1S,2R,4S,5R)-(9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.