Description

4-(3-Bromo-Phenyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, protected piperazine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the piperazine pharmacophore.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require complex amine functionalities.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal complexation.
• Chemical Biology Probes: Employed in the construction of molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A fundamental component for custom synthesis organizations (CSOs) and CDMOs producing bespoke compounds for client projects.
• Academic & Institutional Research: Used in university and institutional labs for methodological development and exploring new chemical spaces.

Basic Information

Product Name	4-(3-Bromo-Phenyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	327030-39-7
Molecular Formula	C15H21BrN2O2
Molecular Weight	341.25 g/mol
Synonyms	1-Boc-4-(3-bromophenyl)piperazine; tert-Butyl 4-(3-bromophenyl)piperazine-1-carboxylate; 4-(3-Bromophenyl)-1-(tert-butoxycarbonyl)piperazine; 1-(tert-Butoxycarbonyl)-4-(3-bromophenyl)piperazine; N-Boc-3-bromophenylpiperazine; 327030-39-7; 4-(3-Bromophenyl)piperazine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 4-(3-Bromo-Phenyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade starting materials and development under ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.