Description

1-(Benzo[D][1,3]Dioxol-5-Ylmethyl)-4-((4-Chlorophenyl)Sulfonyl)Piperazine is a high-purity, synthetic organic compound featuring a piperazine core functionalized with a benzodioxole and a chlorophenylsulfonyl group. This specific molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries. The compound's structure is designed to interact with specific biological targets, facilitating the development of new therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to its benzodioxole moiety.
• Medicinal Chemistry Research: Used as a key scaffold or building block for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Acts as an intermediate in the research and production of new pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Chemical Biology Probe: Employed in the development of molecular probes to study enzyme function or receptor interactions in biological systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	1-(Benzo[D][1,3]Dioxol-5-Ylmethyl)-4-((4-Chlorophenyl)Sulfonyl)Piperazine
CAS No.	326907-59-9
Molecular Formula	C18H19ClN2O4S
Molecular Weight	394.87 g/mol
Synonyms	1-[(1,3-Benzodioxol-5-yl)methyl]-4-[(4-chlorophenyl)sulfonyl]piperazine; 4-((4-Chlorophenyl)sulfonyl)-1-(1,3-benzodioxol-5-ylmethyl)piperazine; 1-(1,3-Benzodioxol-5-ylmethyl)-4-(4-chlorobenzenesulfonyl)piperazine; 4-(4-Chlorophenylsulfonyl)-1-(piperonyl)piperazine; 326907-59-9; UNII-9K1W8FQ14I
EINECS	Contact for details

Quality Control

Our 1-(Benzo[D][1,3]Dioxol-5-Ylmethyl)-4-((4-Chlorophenyl)Sulfonyl)Piperazine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay purity and impurity profiles. Our quality systems are designed to meet the stringent requirements of pharmaceutical intermediate applications, supporting our clients' regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.