Description

(3-Nitrophenyl){4-[(2E)-3-Phenylprop-2-En-1-Yl]Piperazin-1-Yl}Methanone is a specialized organic compound featuring a piperazine core linked to both a 3-nitrophenyl and a cinnamyl-derived moiety. This unique structure makes it a valuable advanced pharmaceutical intermediate and a versatile building block in medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the research and development of new drug candidates, particularly those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Building Block: Used for structure-activity relationship (SAR) studies and lead optimization due to its modifiable piperazine and aromatic nitrogroup.
• Agrochemical Research: Employed in the synthesis of novel compounds with potential herbicidal or insecticidal activity.
• Chemical Biology Probe: Acts as a scaffold for developing molecular probes to study biological pathways and protein interactions.
• Academic & Contract Research: Utilized in university laboratories and CROs (Contract Research Organizations) for exploratory synthetic chemistry projects.

Basic Information

Product Name	(3-Nitrophenyl){4-[(2E)-3-Phenylprop-2-En-1-Yl]Piperazin-1-Yl}Methanone
CAS No.	325779-75-7
Molecular Formula	C20H21N3O3
Molecular Weight	351.40 g/mol
Synonyms	1-[(2E)-3-Phenyl-2-propen-1-yl]-4-(3-nitrobenzoyl)piperazine; (3-Nitrophenyl)[4-[(2E)-3-phenyl-2-propen-1-yl]-1-piperazinyl]methanone; 4-Cinnamyl-1-(3-nitrobenzoyl)piperazine; Methanone, (3-nitrophenyl)[4-[(2E)-3-phenyl-2-propen-1-yl]-1-piperazinyl]-; 325779-75-7
EINECS	Contact for details

Quality Control

Our (3-Nitrophenyl){4-[(2E)-3-Phenylprop-2-En-1-Yl]Piperazin-1-Yl}Methanone is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.