Description

Sn-(3-Myristoyl-2-Hydroxy)-Glycerol-1-Phospho-Sn-3'-(1',2'-Dimyristoyl)-Glycerol (Ammonium Salt) is a high-purity, synthetic phospholipid derivative, specifically a phosphatidylglycerol ammonium salt, essential for advanced formulation science. This compound is critical for creating stable, functional lipid-based delivery systems due to its defined structure and anionic headgroup. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced cosmetics industries for developing liposomes, lipid nanoparticles (LNPs), and other sophisticated biomimetic membranes.

Application

• Lipid Nanoparticle (LNP) Formulation: A key excipient for mRNA and other nucleic acid delivery systems, contributing to particle stability and cellular uptake.
• Liposome & Vesicle Preparation: Used as a component in the lipid bilayer to modulate surface charge, stability, and fusion properties for drug delivery.
• Biomimetic Membrane Research: Serves as a model phospholipid in studies of membrane biophysics, protein-lipid interactions, and membrane fusion processes.
• Pulmonary Surfactant Mimetics: Investigated for use in synthetic lung surfactant formulations due to its structural similarity to natural phospholipids.
• Cosmetic Actives Delivery: Employed in high-end skincare products to enhance the encapsulation and penetration of active ingredients.
• Diagnostic Reagent Development: Used in the formulation of contrast agents or as a component in diagnostic assays requiring specific lipid interfaces.

Basic Information

Product Name	Sn-(3-Myristoyl-2-Hydroxy)-Glycerol-1-Phospho-Sn-3'-(1',2'-Dimyristoyl)-Glycerol (Ammonium Salt)
CAS No.	325466-04-4
Molecular Formula	C40H81NO10P
Molecular Weight	767.04 g/mol
Synonyms	1-Myristoyl-2-hydroxy-sn-glycero-3-phospho-(1'-myristoyl-2'-myristoyl-sn-glycerol) Ammonium Salt; PG(14:0/14:0) Ammonium Salt; 1,2-Dimyristoyl-sn-glycero-3-phospho-(1'-myristoyl-2'-hydroxy-sn-glycerol) Ammonium Salt; Phosphatidylglycerol (14:0/14:0) Ammonium Salt; DMPG-NH4; 1,2-Dimyristoyl-sn-glycero-3-phosphoglycerol (Ammonium Salt); 1-Myristoyl-2-hydroxy-sn-glycero-3-phospho-1',2'-dimyristoyl-sn-glycerol Ammonium Salt
EINECS	Contact for details

Quality Control

Our Sn-(3-Myristoyl-2-Hydroxy)-Glycerol-1-Phospho-Sn-3'-(1',2'-Dimyristoyl)-Glycerol (Ammonium Salt) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and related substances, NMR for structural confirmation, and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical and research applications. Certificates of Analysis (COA) with full traceability are provided.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.