Description

1-Lignoceroyl-2-Hydroxy-Sn-Glycero-3-Phosphocholine is a high-purity, synthetic phospholipid derivative, specifically a lysophosphatidylcholine (LPC) with a very long-chain saturated fatty acid. This compound is a critical biochemical tool and advanced intermediate for research and development in lipidomics and membrane biophysics. It is primarily utilized by scientists and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors. Its defined structure enables precise studies of lipid signaling, membrane asymmetry, and the formulation of sophisticated lipid-based delivery systems.

Application

• Biochemical Research & Lipidomics: Serves as a critical standard and reagent for studying lipid metabolism, cell signaling pathways (e.g., involving lysophosphatidic acid receptors), and membrane dynamics.
• Pharmaceutical Development: Used as a key intermediate or functional excipient in the formulation of advanced drug delivery systems such as liposomes, lipid nanoparticles (LNPs), and niosomes for targeted therapies.
• Cell Culture & Biotechnology: Employed as a component in specialized serum-free media or as an additive to modulate membrane properties and cell signaling in vitro.
• Diagnostic Reagents: Acts as a substrate or calibrant in enzymatic assays and clinical diagnostic kits designed to measure phospholipase activity or specific lipid biomarkers.
• Cosmeceutical Formulations: Incorporated into high-end skincare products for its potential biomimetic properties and role in skin barrier function and repair.
• Biophysical Studies: Essential for creating model membrane systems (e.g., vesicles, bilayers) to investigate lipid-protein interactions, membrane fluidity, and phase behavior.

Basic Information

Item	Detail
Product Name	1-Lignoceroyl-2-Hydroxy-Sn-Glycero-3-Phosphocholine
CAS No.	325171-59-3
Molecular Formula	C32H66NO8P
Molecular Weight	623.85 g/mol
Synonyms	LysoPC(24:0); 1-Tetracosanoyl-2-hydroxy-sn-glycero-3-phosphocholine; Lignoceroyl lysophosphatidylcholine; LPC(24:0); 24:0 LysoPC; 1-(Tetracosanoyl)-2-hydroxy-sn-glycero-3-phosphocholine; sn-Glycero-3-phosphocholine, 1-(tetracosanoyl)-2-hydroxy-; (2R)-2-Hydroxy-3-(trimethylazaniumyl)propyl (tetracosanoyl) phosphate
EINECS	Contact for details

Quality Control

Every batch of 1-Lignoceroyl-2-Hydroxy-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems and undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) detailing key parameters such as assay purity, impurity profile, and confirmation of structure. Our quality commitment aligns with the standards expected for research-grade and GMP-grade biochemicals.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR / NMR)	Conforms to structure
Assay (HPLC)	≥ 95% (Area %)
Purity (TLC)	Single spot
Solubility	Soluble in chloroform, methanol, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.