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1-Palmitoyl-2-(9,10-Dibromo)Stearoyl-Sn-Glycero-3-Phosphocholine CAS NO 324054-52-6
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CAS No.:324054-52-6
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
1-Palmitoyl-2-(9,10-Dibromo)Stearoyl-Sn-Glycero-3-Phosphocholine is a high-purity, synthetic phospholipid derivative, specifically a brominated phosphatidylcholine. This compound is a critical research-grade biochemical for studying membrane biophysics, lipid peroxidation, and oxidative stress mechanisms. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and specialty chemical manufacturers focused on advanced lipidomics and drug delivery system development.
Application
- Biophysical Research: As a key component in model membrane systems (e.g., liposomes, bilayers) to study the effects of lipid bromination on membrane fluidity, permeability, and phase behavior.
- Oxidative Stress Studies: Used as a defined substrate or a biomarker analog to investigate the pathways and consequences of lipid peroxidation in cellular models.
- Pharmaceutical Development: Serves as a specialized raw material or intermediate in the formulation of novel liposomal drug delivery vehicles and diagnostic agents.
- Analytical Standard: Employed as a high-purity reference standard in mass spectrometry (MS) and high-performance liquid chromatography (HPLC) for lipid identification and quantification.
- Biochemical Reagent: Used in enzymatic assays and studies involving phospholipases and other lipid-modifying enzymes to understand substrate specificity.
Basic Information
| Product Name | 1-Palmitoyl-2-(9,10-Dibromo)Stearoyl-Sn-Glycero-3-Phosphocholine |
| CAS No. | 324054-52-6 |
| Molecular Formula | C₄₂H₈₂Br₂NO₈P |
| Molecular Weight | 912.88 g/mol |
| Synonyms | 1-Palmitoyl-2-(9,10-dibromostearoyl)-sn-glycero-3-phosphocholine; PC(16:0/18:0(9,10-diBr)); Brominated Phosphatidylcholine; Dibromostearoyl Phosphatidylcholine; 1-Hexadecanoyl-2-(9,10-dibromooctadecanoyl)-sn-glycero-3-phosphocholine; Br₂-PC; L-α-Phosphatidylcholine, 1-palmitoyl-2-(9,10-dibromostearoyl)- |
| EINECS | Contact for details |
Quality Control
Every batch of our 1-Palmitoyl-2-(9,10-Dibromo)Stearoyl-Sn-Glycero-3-Phosphocholine is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We adhere to stringent in-house specifications suitable for research applications. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC/NMR), identity confirmation, and impurity profile is provided with each shipment to support your quality assurance protocols.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. The product is hygroscopic (moisture-sensitive) and easily oxidized; allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid or waxy solid |
| Identification (HPLC/MS) | Conforms to reference standard |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95% (Area %) |
| Water Content (KF) | ≤ 2.0 % |
| Solvent Residue (GC) | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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