Description

Piperazinone, 6-(Methoxymethyl)-, (6S)- (9Ci) is a chiral piperazinone derivative, a high-value synthetic intermediate characterized by its stereospecific (S)-configuration at the 6-position and a methoxymethyl functional group. This compound matters for its role as a critical building block in the synthesis of complex, biologically active molecules, where its specific stereochemistry is essential for efficacy. It is primarily needed by pharmaceutical R&D and process chemistry teams developing novel therapeutics, particularly in areas requiring chiral amine scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or precursor in asymmetric synthesis to introduce stereocenters into complex organic molecules.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and library synthesis for drug discovery programs targeting specific receptors or enzymes.
• Process Chemistry & Scale-Up: Acts as a starting material or intermediate in the optimization and commercial-scale production of chiral drugs.
• Chemical Biology Probes: Used in the design and synthesis of chemical probes for studying biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: A critical component for fine chemical suppliers offering bespoke synthesis services for the life sciences industry.

Basic Information

Product Name	Piperazinone, 6-(Methoxymethyl)-, (6S)- (9Ci)
CAS No.	323592-70-7
Molecular Formula	C7H14N2O2
Molecular Weight	158.20 g/mol
Synonyms	(6S)-6-(Methoxymethyl)piperazin-2-one; (S)-6-(Methoxymethyl)piperazin-2-one; (S)-6-(Methoxymethyl)-2-piperazinone; 2-Piperazinone, 6-(methoxymethyl)-, (6S)-; (6S)-6-(Methoxymethyl)-1,4-diazinan-2-one; 323592-70-7; (S)-6-Methoxymethyl-piperazin-2-one
EINECS	Contact for details

Quality Control

Our Piperazinone, 6-(Methoxymethyl)-, (6S)- (9Ci) is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to confirm identity and specification compliance. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.