Description

(S)-6-Methyl-Piperazin-2-One is a high-purity chiral piperazinone derivative, a crucial building block in modern pharmaceutical synthesis. Its enantiomeric purity and defined stereochemistry make it an essential intermediate for developing active pharmaceutical ingredients (APIs) with specific biological activity. This compound is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, particularly in areas requiring sophisticated chiral scaffolds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of novel drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Asymmetric Synthesis: Serves as a versatile building block in asymmetric synthesis for constructing complex molecules with defined stereocenters.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery pipelines.
• API Development: An intermediate in the synthesis of more complex Active Pharmaceutical Ingredients (APIs) that incorporate the piperazinone pharmacophore.
• Chemical Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in pharmaceutical manufacturing.

Basic Information

Product Name	(S)-6-Methyl-Piperazin-2-One
CAS No.	323592-68-3
Molecular Formula	C5H10N2O
Molecular Weight	114.15 g/mol
Synonyms	(S)-6-Methyl-2-piperazinone; (S)-6-Methylpiperazin-2-one; (S)-6-Methyl-1,4-diazinan-2-one; (S)-6-Methyl-2-ketopiperazine; (S)-6-Methyl-2-oxopiperazine; (S)-6-Methylpiperazine-2-one; (S)-6-Methyl-2-piperazinone; (S)-6-Methyl-2-piperazinone
EINECS	Contact for details

Quality Control

Our (S)-6-Methyl-Piperazin-2-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, NMR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure containers are kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.