Description

Piperazinone, 6-(2-Methylpropyl)-, (6R)- (9Ci) is a chiral piperazinone derivative, a high-value synthetic intermediate characterized by its specific stereochemistry at the 6-position. This compound is critical for pharmaceutical research and development, enabling the synthesis of complex molecules with targeted biological activity. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications in medicinal chemistry and asymmetric synthesis.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral research.
• Medicinal Chemistry: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Asymmetric Synthesis: Serves as a precursor or scaffold for constructing complex, enantiomerically pure molecules due to its defined (6R) configuration.
• Agrochemical Research: Potential intermediate in the development of new, selective pesticides and herbicides.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for specialized, high-value chemical products.
• Academic & Institutional Research: Used in university and institutional labs for methodological development and biochemical studies.

Basic Information

Product Name	Piperazinone, 6-(2-Methylpropyl)-, (6R)- (9Ci)
CAS No.	323592-66-1
Molecular Formula	C8H16N2O
Molecular Weight	156.23 g/mol
Synonyms	(6R)-6-(2-Methylpropyl)piperazin-2-one; (R)-6-Isobutylpiperazin-2-one; 6-Isobutyl-2-piperazinone, (R)-; (R)-6-(2-Methylpropyl)-2-piperazinone; 323592-66-1; (6R)-6-(2-Methylpropyl)piperazinone; (R)-6-Isobutyl-2-piperazinone
EINECS	Contact for details

Quality Control

Our Piperazinone, 6-(2-Methylpropyl)-, (6R)- (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.