Description

4-tert-Butoxycarbonylamino-1-(4-Aminobenzyl)Piperidine is a high-purity, bifunctional piperidine derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a Boc-protected amine and a primary aromatic amine, makes it an exceptionally versatile intermediate for constructing complex pharmacologically active molecules. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new chemical entities, particularly for creating libraries of potential drug candidates and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel small molecule drugs, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Peptidomimetic Scaffold: Used to construct peptidomimetics and conformationally constrained peptide analogs, leveraging the piperidine ring as a rigid backbone.
• Ligand and Receptor Probe Development: Serves as a core structure for developing high-affinity ligands for biological target validation and biochemical assay development.
• Chemical Biology Tool Compound: Employed in the synthesis of chemical probes for studying enzyme function and protein-protein interactions within biological systems.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing non-commercial, research-scale compounds under cGMP conditions.
• Library Synthesis for High-Throughput Screening (HTS): Facilitates the rapid generation of diverse compound libraries for screening against novel biological targets.

Basic Information

Product Name	4-tert-Butoxycarbonylamino-1-(4-Aminobenzyl)Piperidine
CAS No.	323578-56-9
Molecular Formula	C17H27N3O2
Molecular Weight	305.42 g/mol
Synonyms	1-(4-Aminobenzyl)-4-[(tert-butoxycarbonyl)amino]piperidine; 4-(Boc-amino)-1-(4-aminobenzyl)piperidine; 4-(N-Boc-amino)-1-(4-aminobenzyl)piperidine; 1-(4-Aminophenylmethyl)-4-[(tert-butoxycarbonyl)amino]piperidine; tert-Butyl N-[1-[(4-aminophenyl)methyl]piperidin-4-yl]carbamate; 4-tert-Butoxycarbonylamino-1-(4-aminobenzyl)piperidine; Boc-4-amino-1-(4-aminobenzyl)piperidine
EINECS	Contact for details

Quality Control

Our 4-tert-Butoxycarbonylamino-1-(4-Aminobenzyl)Piperidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical development. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications. We support development projects requiring material produced under ICH Q7 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere or inert gas to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.