Description

1,2-Dioctanoyl-Sn-Glycero-3-Phospho-(1'-Rac-Glycerol) (Sodium Salt) is a high-purity, synthetic phospholipid derivative, specifically a sodium salt of a phosphatidylglycerol analog with medium-chain fatty acids. This compound is critical for research and development in advanced lipid-based delivery systems due to its defined structure and consistent quality. It is primarily needed by pharmaceutical researchers, formulation scientists, and manufacturers working on liposomes, lipid nanoparticles (LNPs), and other biomimetic membranes for drug delivery, diagnostics, and cosmetic applications.

Application

• Liposome and Lipid Nanoparticle (LNP) Formulation: Serves as a key excipient or structural lipid to modulate membrane fluidity, stability, and surface charge in drug delivery vehicles for mRNA, siRNA, and small molecule therapeutics.
• Biomimetic Membrane Research: Used in the construction of model membranes and vesicles (e.g., giant unilamellar vesicles) for studying lipid-protein interactions, membrane permeability, and biophysical properties.
• Pulmonary Surfactant Research: Investigated as a synthetic component in models of lung surfactant for respiratory research and potential therapeutic development.
• Cosmetic and Dermal Delivery Systems: Employed in the formulation of advanced cosmetic products and transdermal delivery systems to enhance skin penetration and stability of active ingredients.
• Diagnostic Reagent Development: Utilized in the preparation of calibration standards, assay components, or as a coating material in various diagnostic platforms.
• Biochemical and Cell Biology Studies: Acts as a substrate or modulator in enzymatic assays, signal transduction studies, and cell culture applications.

Basic Information

Product Name	1,2-Dioctanoyl-Sn-Glycero-3-Phospho-(1'-Rac-Glycerol) (Sodium Salt)
CAS No.	322647-21-2
Molecular Formula	C22H42NaO10P
Molecular Weight	520.52 g/mol
Synonyms	Sodium 1,2-Di-O-octanoyl-sn-glycero-3-phospho-(1'-rac-glycerol); 1,2-Di-O-octanoyl-sn-glycero-3-phospho-(1'-rac-glycerol) Sodium Salt; PG(C8:0/C8:0) Sodium Salt; Phosphatidylglycerol (C8:0) Sodium Salt; 1,2-Dicapryloyl-sn-glycero-3-phosphoglycerol Sodium Salt; Dioctanoyl Phosphatidylglycerol Sodium; DCPG-Na; 1,2-Dioctanoylphosphatidylglycerol Sodium Salt
EINECS	Contact for details

Quality Control

Our 1,2-Dioctanoyl-Sn-Glycero-3-Phospho-(1'-Rac-Glycerol) (Sodium Salt) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and life science research. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). For long-term storage, keep containers sealed under an inert atmosphere. Allow the product to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.