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1,2-Dioctanoyl-Sn-Glycero-3-Phosphate (Sodium Salt) CAS NO 321883-54-9
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CAS No.:321883-54-9
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
1,2-Dioctanoyl-Sn-Glycero-3-Phosphate (Sodium Salt) is a synthetic, anionic phospholipid derivative, a critical component in the formulation of advanced lipid-based delivery systems. This compound is valued for its role as a functional excipient that enhances the stability and bioavailability of encapsulated active ingredients. It is primarily required by pharmaceutical, cosmetic, and life science research industries for developing liposomes, nanoemulsions, and other sophisticated drug delivery platforms.
Application
- Liposome & Lipid Nanoparticle (LNP) Formulation: A key structural and functional phospholipid for constructing stable vesicles for drug and gene delivery (e.g., mRNA vaccines).
- Biomimetic Membrane Research: Used to create model membrane systems for studying protein-lipid interactions, membrane permeability, and cell signaling.
- Cosmetic Nano-carriers: Employed in high-end skincare products to encapsulate and improve the penetration of active ingredients like vitamins and antioxidants.
- Diagnostic Reagents: Serves as a component in diagnostic kits and assays that utilize liposomal technology for signal amplification.
- Pharmaceutical Excipient: Functions as a solubilizer and stabilizer in injectable and topical pharmaceutical formulations.
- Biochemical Research: A substrate or intermediate in enzymatic studies related to phospholipid metabolism and signaling pathways.
Basic Information
| Product Name | 1,2-Dioctanoyl-Sn-Glycero-3-Phosphate (Sodium Salt) |
| CAS No. | 321883-54-9 |
| Molecular Formula | C19H36NaO8P |
| Molecular Weight | 446.45 g/mol |
| Synonyms | 1,2-Di-O-octanoyl-sn-glycero-3-phosphate sodium salt; Sodium 1,2-dioctanoyl-sn-glycero-3-phosphate; Dioctanoyl phosphatidic acid sodium salt; PA(8:0/8:0) sodium salt; 1,2-Di-C8:0 PA sodium salt; sn-Glycero-3-phosphoric acid 1,2-dioctanoate sodium salt; Phosphatidic acid (diC8) sodium salt; C8 Phosphatidic Acid Sodium Salt |
| EINECS | Contact for details |
Quality Control
Our 1,2-Dioctanoyl-Sn-Glycero-3-Phosphate (Sodium Salt) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing purity, residual solvents, and other critical parameters is provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder or solid |
| Identification (IR & NMR) | Conforms to structure |
| Assay (HPLC) | ≥ 95.0% |
| Water Content (KF) | ≤ 5.0% |
| Residual Solvents (GC) | Meets ICH guidelines |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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