Description

1,2-Didecanoyl-Sn-Glycero-3-Phospho-L-Serine (Sodium Salt) is a high-purity, synthetic phospholipid derivative, specifically a phosphatidylserine (PS) species with defined decanoyl (C10:0) fatty acid chains. This compound is critical for research and development in advanced drug delivery systems, particularly in the formulation of liposomes and lipid nanoparticles (LNPs) for targeted therapeutic applications. It is essential for scientists and manufacturers in the pharmaceutical, biotechnology, and life science sectors who require precisely characterized lipid components for membrane studies, diagnostic assays, and next-generation nanomedicines.

Application

• Liposome & Lipid Nanoparticle (LNP) Formulation: A key excipient for creating stable, anionic liposomal vesicles used in drug delivery, mRNA vaccines, and gene therapy.
• Membrane Biology & Biophysics Research: Used as a standard or model lipid to study membrane asymmetry, protein-lipid interactions, and apoptosis signaling in cell membranes.
• Diagnostic Reagent Preparation: Employed in the development of diagnostic kits and assays that detect phospholipid-dependent processes, such as blood coagulation tests.
• Cell Culture & Neuroscience Studies: Serves as a supplement to investigate the role of phosphatidylserine in neuronal function, cognitive health, and cellular repair mechanisms.
• Pharmaceutical Reference Standard: Acts as a certified reference material (CRM) for quality control and analytical method development in lipid-based product manufacturing.
• Cosmetic & Dermal Delivery Systems: Incorporated into nano-carriers for enhanced skin penetration and stabilization of active ingredients in cosmetic formulations.

Basic Information

Product Name	1,2-Didecanoyl-Sn-Glycero-3-Phospho-L-Serine (Sodium Salt)
CAS No.	321863-22-3
Molecular Formula	C26H49NNaO10P
Molecular Weight	589.64 g/mol
Synonyms	PS(10:0/10:0); 1,2-Dicapryloyl-sn-glycero-3-phospho-L-serine (sodium salt); L-α-Phosphatidylserine, 1,2-didecanoyl- (sodium salt); DOPS (10:0); Phosphatidylserine (Decanoyl); Sodium 1,2-bis(decanoyloxy)-3-[(R)-2-amino-3-hydroxy-propoxy-hydroxy-phosphoryl]oxy-propyl phosphate
EINECS	Contact for details

Quality Control

Our 1,2-Didecanoyl-Sn-Glycero-3-Phospho-L-Serine (Sodium Salt) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and research applications. Comprehensive Certificates of Analysis (COA) detailing purity, residual solvents, and other critical parameters are provided to guarantee traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, keep containers in a dry, inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.