Description

Piperazine, 1-(5-Hexynyl)-4-Methyl- (9Ci) is a specialized piperazine derivative featuring a terminal alkyne functional group. This unique molecular architecture makes it a versatile building block for the synthesis of complex nitrogen-containing heterocycles and pharmaceutical intermediates. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors for applications in medicinal chemistry and chemical biology.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Click Chemistry Reagent: The terminal alkyne group enables efficient, high-yielding Huisgen 1,3-dipolar cycloaddition reactions with azides for bioconjugation and polymer synthesis.
• Ligand Synthesis: Used to create complex chelating ligands for catalysis and metal-organic framework (MOF) construction.
• Agrochemical Research: Employed in the development of new active ingredients for crop protection products.
• Chemical Biology Probes: Facilitates the creation of tagged molecules for studying biological pathways and protein interactions.
• Polymer Modification: Acts as a functional monomer or cross-linking agent to introduce piperazine moieties into polymer backbones.

Basic Information

Product Name	Piperazine, 1-(5-Hexynyl)-4-Methyl- (9Ci)
CAS No.	320366-90-3
Molecular Formula	C11H20N2
Molecular Weight	180.29 g/mol
Synonyms	1-(5-Hexynyl)-4-methylpiperazine; 4-Methyl-1-(5-hexynyl)piperazine; 1-Methyl-4-(5-hexyn-1-yl)piperazine; N-(5-Hexynyl)-N'-methylpiperazine; Piperazine, 1-(5-hexynyl)-4-methyl-; 320366-90-3; 1-(5-Hexyn-1-yl)-4-methylpiperazine
EINECS	Contact for details

Quality Control

Our high-purity piperazine derivative is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes. We support cGMP compliance for advanced research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.